Overlap connective tissue syndromes.

Overlap connective tissue syndromes.

Twenty six children with overlapping features of more than one connective tissue disorder are reported. The median age of onset was 9.5 years and median duration of follow up 7.5 years. Common presenting symptoms included arthritis, tenosynovitis. Raynaud's phenomenon, myositis, and rashes. At follow up 14 patients had developed sclerodermatous skin changes, but significant systemic involvement...

[Polymyositis, dematomyositis: overlap syndromes with connective tissue diseases and malignancies].

Polymyositis and Dermatomyositis are often connected with autoimmune diseases and are closely linked with specific autoantibodies. Clinical manifestations are mild in correlation with clinical picture ofmyositis related to malignancy. Pulmonary complications are main cause of mortality in overlap syndromes with autoimmune diseases. Infection, cardiovascular complications and underlying malignan...

Mixed connective tissue disease, overlap syndromes, and eosinophilic fasciitis.

While the cause of connective tissue diseases (CTDs) remains unknown the classification of individual patients will continue to depend on identifying certain patterns of clinical and laboratory features. This is the basis of the various classification criteria for systemic sclerosis,'l systemic lupus erythematosus (SLE),2 and other connective tissue diseases. As many as 25% of patients with CTD...

'Overlap' syndromes.

Many of us at the end of a weekly lupus clinic are tempted to reflect that almost all shades of connective tissue 'overlap' occur, and that it is perhaps pointless to attempt too precise a definition in individual cases. The introduction of the concept of overlap syndromes was a pragmatic way to resolve an imprecise compromise. It represented an attempt to categorise various groups of disorders...

Urticarial vasculitis and syndromes in association with connective tissue diseases.